AICAR’s primary function is to activate AMPK (AMP-activated protein kinase), thereby exhibiting various activities in cell and animal models, including anticancer, antihypertensive, antidiabetic, and anti-inflammatory effects. It can also promote glucose uptake in skeletal muscle, regulate metabolism, inhibit pro-inflammatory factors, and enhance the efficacy of other drugs.
AICAR’s primary function is to activate AMPK (AMP-activated protein kinase), thereby exhibiting various activities in cell and animal models, including anticancer, antihypertensive, antidiabetic, and anti-inflammatory effects. It can also promote glucose uptake in skeletal muscle, regulate metabolism, inhibit pro-inflammatory factors, and enhance the efficacy of other drugs.
Promoting Glucose Metabolism: AICAR can activate AMPK, thereby promoting non-insulin-dependent glucose uptake in skeletal muscle and helping to regulate blood sugar levels.
Anti-inflammatory Effects: AICAR can inhibit the production of pro-inflammatory factors and nitric oxide synthase (iNOS), thus exerting an anti-inflammatory effect.
Anticancer Activity: AICAR possesses anticancer activity, enhancing the effects of other anticancer drugs (such as rapamycin) and inhibiting signal transduction in certain cancer cells (such as breast cancer cells).
Improving Cardiovascular Health: Studies have shown that AICAR can lower arterial pressure and induce vasodilation, which is beneficial to cardiovascular health.
Regulating Metabolism: AICAR can regulate glucose and lipid metabolism and may improve energy utilization efficiency by activating AMPK.
None of our HGH lines are inherently better than the other. Each batch comes with a corresponding test report. Purity and dimer can be a decent proxy for “quality”, you want purity as high as possible and dimer as low as possible. The main factor to consider in our opinion, is the price per IU. Supreme is usually the best bang for buck option. Historically, Supreme & Deluxe have shown lower dimer content, although this may not always be the case, so of course reference the corresponding test reports.
For HGH, we typically recommend 1ml for every ~10 IU in the vial. If a batch tests at an average of 290 IU per kit, that is an average of 29 IU per vial, and we’d recommend 2.9ml of bacteriostatic water. This will make the syringe math similar to a traditional 100 iu kit with 1ml of solution For peptide reconstituion, you can use our amazing Dosage Calculator.
Not necessarily. If you look through all our lab reports, particularly the ones with multiple test reports in a single batch, you will see that the intra-batch variance can actually be quite high. When you purchase a batch, you can expect some of the vials in your kit to be as much as 5-15% +/- whatever the corresponding lab test reflects. This is simply the reality of product that is not made to the same standards as pharmaceutical grade growth hormone. To state otherwise would be disingenous. There can also be a high variance in the dimer content intra-batch. (For Example: Economy B, Deluxe A, etc) Over time, we’ve increased the volume of samples analyzed for each batch, to provide more transparancy regarding the potential for intra-batch variance. If you use the average IU figure provided on each product, your dosage should average out over time, so don’t overthink your administration protocol too much. We know it can be a bit overwhelming with all the different numbers provided. That said, don’t hesitate to reach out if you need specific guidance on dosage or reconstitution.
Yes! We offer store credit for quantitative testing of total IU/Purity (ie Janoshik testing), and for personal IGF-1 test results. Please email for more information. *TERMS APPLY*
Depending on your location, most customers receive their order in 2-10 business days. We ship with USPS Ground Shipping, from the United States only. 99% of orders ship within 24 hours (excluding weekends & holidays)
We are no longer providing tracking. If your order is over 10 business days old and hasn’t arrived, our customer service team can check your tracking information to see the status of your package
If your order was marked as “completed”, typically this means a label has been generated and your order is scheduled to go out that day or the next. “Processing” status orders have not been shipped, processing means payment has been confirmed successfully. Don’t hesitate to reach out regarding the status of your order.
Unfortunately we do not provide reships for incorrect addresses. In the VERY rare instance that a package is lost in transit, we will reship your order free of charge.
MT1 is a melatonin receptor that regulates the body’s circadian rhythms and sleep cycles by binding to melatonin. It is expressed in the central nervous system and retina, and its main role is to mediate and regulate circadian rhythms, sleep initiation, and maintenance. Therefore, it is closely related to the development of melatonin and drugs containing MT1/MT2 receptor agonists, such as those used to treat insomnia and depression. Furthermore, MT1 is also associated with anti-inflammatory and antioxidant effects, particularly in activated macrophages and microglia.
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Epitalon, also known as Epithalon or Epithalone, is a tetrapeptide, Ala-Glu-Asp-Gly (AEDG), which was synthesized based on the amino acids composition of Epithalamin, a bovine pineal gland extract, prior to its discovery in pineal gland polypeptide complex solution. During the last 25 years, this compound has been extensively studied using in vitro, in vivo, and in silico methods. The results of these studies indicate significant geroprotective and neuroendocrine effects of Epitalone, resulting from its antioxidant, neuro-protective, and antimutagenic effects, originating from both specific and nonspecific mechanisms. Although it has been demonstrated that Epitalon exerts, among other effects, a direct influence on melatonin synthesis, alters the mRNA levels of interleukin-2, modulates the mitogenic activity of murine thymocytes, and enhances the activity of various enzymes, including AChE, BuChE, and telomerase, it remains uncertain whether these are the sole mechanisms of action of this compound. Moreover, despite the considerable volume of research on the biological and pharmacodynamic characteristics of Epitalon, the quantity of physico-chemical and structural investigations of this peptide remains quite limited. This review aims to conclude the most important findings from such studies, thus presenting the current state of knowledge on Epitalon.
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FOXO4 peptide refers to a polypeptide that mimics or blocks the FOXO4 transcription factor. Its main function is to induce the apoptosis of senescent cells (removal of senescent cells) selectively, thereby achieving the purpose of anti-aging and treating related diseases. These peptide types, such as FOXO4-DRI, can block the interaction between FOXO4 and p53, thereby selectively eliminating senescent cells and improving tissue function and healthy lifespan.
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Oxytocin’s main functions include promoting uterine contractions and lactation during childbirth and lactation; in social behavior, it enhances intimacy, trust, and mother-infant attachment, hence its nickname “love hormone”; it can also help relieve stress and pain, and may have potential therapeutic effects on mental health issues such as autism.
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